PIWI Takes a Giant Step
نویسندگان
چکیده
piRNA guides the action of PIWI proteins to silence deleterious transposons in animal reproductive tissues. Biogenesis of piRNA-induced silencing complex (piRISC) involves a multi-step process. In this issue, Matsumoto et al. report the first crystal structure of a PIWI-clade protein displaying a guide RNA, ready for action.
منابع مشابه
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عنوان ژورنال:
- Cell
دوره 167 شماره
صفحات -
تاریخ انتشار 2016